Cancer mainly develops through various deregulated processes, including uncontrolled regulation of the cell cycle progression, apoptosis evasion due to the expression of anti-apoptotic proteins overcoming pro-apoptotic protein expression, and dysregulation of DNA repair mechanism due to altered tumor suppressor gene p53 (Feitelson et al., 2015; Marei et al., 2021). This evidence concerns the gene TP53 and cancer.