Upregulation of E-cadherin (1.82-fold, p = 0.00092 for HT29, Figure 3G; 1.5-fold, p = 0.00091 for SW620, Figure 3I) and downregulation of N-cadherin (0.19-fold, p = 0.000124 for HT29, Figure 3G; 0.15-fold, p = 0.000011 for SW620, Figure 3I) expressions in both CRC cells exposed to Compound 5a (10 μM) were confirmed at the gene expression level using RT-qPCR, compared with the basal gene expression level monitored in the untreated cells (Figure 3). The gene discussed is CDH2; the disease is colorectal carcinoma.