It was reported that PL significantly induced apoptosis and cell death in ABC-DLBCL cell lines via suppression of NF-κB signaling pathway and modulating the NF-κB-mediated proteins responsible for apoptosis and cell survival such as Bcl-2, survivin, Bax, and p21 [122]. Here, NFKB1 is linked to diffuse large B-cell lymphoma.