Compared to that in the normal kidney cells, the NK(EGR1) and NK(CAPG) subpopulations were abnormally elevated in ccRCC and could mediate ccRCC metastasis, such as Hodgkin's lymphoma, T-cell leukaemia, and Ki-1+ anaplastic large cell lymphoma development in kidney cancer (Figures 4(c) and 4(d)). This evidence concerns the gene TNFRSF8 and kidney cancer.