And the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses indicated that the differentially expressed interleukin 17B (IL-17B) in IVC tissues during thrombosis was significantly associated with the RIP3/MLKL signaling pathway, but the regulation effect o thef IL-17B RIP3/MLKL pathway in acute DVT remains unknown. The gene discussed is RIPK3; the disease is Venous thrombosis.