CCK and Anxiety: Additionally, Smarca3 KO or Neurensin-2 overexpression in CCK interneurons (CCK-Cre line), but not PV neurons, in the dentate gyrus causes depressive- and anxiety-like behavioral phenotypes in TST, FST, SPT, cookie test, social interaction test, and OFT (Umschweif et al., 2021b), although CCK-p11 KO did not display baseline depressive-like behavior in the TST and FST (Medrihan et al., 2017).