Also, our results showed that M2-CM increased the expression levels of mesenchymal biomarkers (N-cadherin, Slug, and Twist), whereas downregulated epithelial marker (E-cadherin) to promote epithelial-mesenchymal transition (EMT) in GBM cells (Figures 3(f) and 3(g)). Here, CDH2 is linked to glioblastoma.