The OS and the methylation of PDIA3 promoter region were analyzed, and the results showed that in BLCA, BRCA, KICH, and THYM, the methylation level of PDIA3 promoter region was the protective factor of overall survival rate, while in LIHC, the methylation level of PDIA3 was negatively correlated with OS, and the higher the methylation level of PDIA3, the worse the prognosis (Figure 13(b)). Here, PDIA3 is linked to bladder transitional cell carcinoma.