The expression levels of RIPK3, RIPK1, ox-CaMKII, p-CaMKII, MLKL, P-MLKL, cleaved-caspase3, and caspase3 protein in AngII-induced cardiac hypertrophy WT mice were significantly increased (P < 0.05) in WT (AMP-AngII) compared with the NS group. Here, RIPK1 is linked to cardiac hypertrophy.