Echocardiography was performed for RIPK3-KO (RIPK3−/−) mice with myocardial hypertrophy, and it was observed that the cardiac systolic and diastolic functions were significantly improved when compared to the WT (AMP-AngII) group; cardiac ejection fraction (EF) and short-axis shortening rate (FS) were significantly increased (P < 0.05) (Figures 3(a) and 3(b)). This evidence concerns the gene RIPK3 and cardiac hypertrophy.