Another study by Diana Aguilar-Morante et al. found that C/EBPβ (Enhancer Binding Protein β) could increase S100A4 levels by activating S100A4 promoter expression directly in murine GL261 and human T98G glioblastoma cells, and their data indicated that S100A4 play a crucial role of cell invasion and could mediate the observed effects of C/EBPβ on invasiveness of glioblastoma cells 25 (Table 1). This evidence concerns the gene S100A4 and glioblastoma.