S100B and astrocytoma (excluding glioblastoma): Flora Brozzi, et al. analyzed the effects of inhibition S100B expression in astrocytoma cell line GL15 and the Müller cell line MIO-M1 by knockdown S100B gene expression with small interference RNA technique, these results suggest that S100B might involve in the regulation of cell morphology, differentiation and migration through src-dependent activation of PI3K 27.