As shown in Figure 1, we observed that nine genes were involved in the DEGs of AML overexpression, ferroptosis-suppression genes, and ferroptosis-related genes obtained from the GeneCards database (CD44, ZFP36, TP53, HMOX1, ARNTL, HIF1A, AKR1C3, HELLS, and RB1). The gene discussed is HIF1A; the disease is acute myeloid leukemia.