STIM1 and lung cancer: Heretofore, Wang, et al. [49] identified that STIM1 was significantly overexpressed in lung cancer tissues as compared to that of non-neoplastic lung tissues; furthermore, Ge, et al. [50] revealed that STIM1 knockdown induced cell cycle arrest at G2/M and S phases through alleviating expression of CDK1 and 2 in A549 and SK-MES-1 cells, and abolishing tumorigenesis and growth of lung cancer cells in nude mice xenograft.