Among patients with PD-L1 positive tumors (at least 1% of total tumor area occupied by positive immune cells by using the Ventana SP142 IHC assay), the median PFS was 7.5 months and 5.0 months, respectively (HR 0.62, 95% CI 0.49–0.78, P < 0.001) [12]. The gene discussed is CD274; the disease is neoplasm.