As at present, there is no evidence about the involvement of Bcl2L10 in melanomaprogression, the current study aims at investigating whether Bcl2L10 affectsproperties known to be associated with tumor aggressiveness, such as invitro and in vivo tumor growth as well as migration,invasion and capillary-like structure formation [vasculogenic mimicry(VM)]. This evidence concerns the gene BCL2L10 and neoplasm.