The most frequent grade was NET grade 1 (54 cases, 62%), followed by NET grade 2 (21 cases, 24.1%), NET grade 3 (nine cases, 10.3%), which included both NET (three cases) and NEC (six cases), and MINENs (three cases, 3.5%). Immunohistochemical stain Synaptophysin was positive in 73 out of 87 cases (83.9%) while Chromogranin A was positive in 34 out of 87 cases (39.1%). This evidence concerns the gene SYP and neuroendocrine carcinoma.