The waterfall plot for all STAD patients in the study showed that the top ten most mutated genes are TTN, TP53, MUC16, ARIDIA, LRPIB, SYNE1, FLG, CSMD3, FAT4, and PCLO, and 19% of the patients carried FLG mutation. The gene discussed is CSMD3; the disease is gastric adenocarcinoma.