DUXAP8 exerts an essential role in tumorigenesis, proliferation, migration, invasion, and inhibition of apoptosis, which means that DUXAP8 acts as an oncogene in the occurrence and development of various malignant tumors (Jiang et al., 2019; Hu et al., 2020; Wang et al., 2020; Wei et al., 2020; Zhang et al., 2020; Guan et al., 2021). Here, DUXAP8 is linked to cancer.