VWF and COVID-19: A report by Goshua et al from Yale University examined blood samples of COVID-19 patients (those critically ill in an (ICU) and others receiving care but in a non-ICU unit) and disease-free volunteers.93, 95Specifically, they compared biomarkers of endothelial cell and platelet activation, including sTM, von Willebrand's factor (vWF) antigen, soluble P-selectin, and soluble CD40 ligand, as well as coagulation factors, endogenous anticoagulants, and fibrinolytic enzymes.