NEFL and neurodegenerative disease: Finally, it would be necessary for those with cognitive impairment to evaluate biomarkers of neurodegenerative diseases in cerebrospinal fluid or plasma, such as amyloid Beta 1–42, phosphorylated tau, and light chain neurofilament, thus bringing a link between COVID-19 and the onset or worsening of neurodegenerative diseases (60, 61).