In both in vitro and murine model studies, Almasi et al. [184] suggested that TRPM2 promoted gastric-cancer migration, invasion, and tumor growth through the AKT pathway; the same group previously demonstrated that TRPM2 promoted gastric-cancer cell survival via the c-Jun NH2-terminal kinase (JNK) pathway [185]. The gene discussed is MAPK8; the disease is neoplasm.