We identified a high confidence list of 236 genes, common MM driver mutations (i.e. TP53, KRAS, NRAS, ATM and CCND1) and novel mutated genes belonging to JAK-STAT, PI(3)K-AKT, DNA repair and chromatin modifier pathways, with a focus on their correlation to drug response [175]. Here, NRAS is linked to Miyoshi myopathy.