For hematological test, CA199 in patients with lymph node metastasis (16.256 ± 9.732 U/ml) was significantly higher than that in patients without lymph node metastasis (12.382 ± 8.542 U/ml), while tissue polypeptide specific antigen (TPS) and carcinoembryonic antigen (CEA) showed no statistical difference between patients of two groups (p > 0.05). Here, CEACAM5 is linked to metastatic malignant neoplasm in the lymph nodes.