These data are supported by clinical tumor data from TCGA (Figure 4), which reveal that in human GBM tumors, TRAF3IP2 expression as well as VEGF, IL6, ANGPT2, IL8, PGF, IL1b, ITGAV, and VEGFR2 are significantly upregulated compared to normal tissue. This evidence concerns the gene IL6 and glioblastoma.