WNT6 and cancer: Among the DEGs in PA, we identified enrichment in cancer pathways (e.g., basal cell carcinoma) among the most relevant KEGG pathways, and significant downregulation of growth-related genes such as Wnt6 (Wnt Family Member 6, FC = −2.019, p = 4.18E-05) and FZD5 (frizzled-5, FC = −1.493, p = 0.0001).