In the future, we could study the correlation between the memory function of CD4+ T cells, CD4+/CD8+, and visual space domain and memory T cells (CD4+ CD45RO+ T cells, CD8+ CD28− T cells) to explore the mechanism of accelerated immune aging and cognitive impairment in patients with SLE, especially in attention disorder, memory, and visual space domain. Here, CD8A is linked to systemic lupus erythematosus.