CD8A and Cognitive impairment: In the future, we could study the correlation between the memory function of CD4+ T cells, CD4+/CD8+, and visual space domain and memory T cells (CD4+ CD45RO+ T cells, CD8+ CD28− T cells) to explore the mechanism of accelerated immune aging and cognitive impairment in patients with SLE, especially in attention disorder, memory, and visual space domain.