Further GSEA analyses based on a single gene expression indicated that B-cell-mediated immunity, complement cascade, interferon-gamma response, chromosome segregation, mitotic spindle checkpoint, G2M checkpoint, T-cell receptor complex, CD22-mediated BCR regulation, epithelial–mesenchymal transition, cell cycle checkpoints, voltage-gated potassium channels, and other biological processes related to immunity or cancer were significantly enriched (Supplementary Figure 6). Here, CD22 is linked to cancer.