LIAS and neoplasm: Twelve CRGs were upregulated in tumor samples including FDX1, LIPT1, LIAS, DLD, DBT1, GCSH, DLST, DLAT, PDHA1, PDHB, SLC31A1, and ATP7A (P< 0.001), whereas only ATP7B was downregulated (P< 0.001) (Figure 2G).