ROC analysis revealed that AUC values for the ability of CD69, SBK1 and RN7SK to predict response to PD-1/PD-L1 blockade immunotherapy in lung cancer were 0.754, 0.803, and 0.797, respectively (Figures 2B–D), while in melanoma they were 0.637, 0.668, and 0.597, respectively (Figures 2E–G). The gene discussed is CD274; the disease is melanoma.