IGHE and achondroplasia: Among them, compared with the SGMH group, there were significant differences in IgE, IL-4, IL-13, SP, PGE2, and CGRP in the ACH group (Figures 4(a)–4(f)) (P < 0.001, P < 0.05), IL-4 had a statistical difference in the BCH group (Figure 4(b)) (P < 0.001).