Lastly, the underlying pathology of FTD can be one of three forms: cellular inclusions containing abnormal forms of tau, TAR DNA-binding protein 43 (TDP-43), or FET proteins (fused in sarcoma (FUS), Ewing sarcoma (EWS), and TATA-binding associated factor 15 (TAF15)) [4]. The gene discussed is TARDBP; the disease is frontotemporal dementia.