Further validation experiments demonstrated that circSMARCC1 may serve as an endogenous miRNA sponge to inhibit the expression of miR-1322 by binding to miR-1322 in PCa cells, resulting in alleviating the inhibitory effect of miR-1322 on CCL20 and ultimately promotes PCa cell proliferation and metastasis. The gene discussed is CCL20; the disease is posterior cortical atrophy.