Conversely, we found the previously identified PCa driver gene LRP1B (12/17) and new candidate genes TTC28 (16/27), CADM2 (12/16), LSAMP (11/16), EYS (16/18), PTPRD (12/18), PACRG (5/6) and PDE4D (12/17) to be predominately interrupted in tumours from African patients. The gene discussed is LRP1B; the disease is posterior cortical atrophy.