TMPRSS2 and cancer: Investigating TMPRSS2-ERG and their alternative partners revealed six (out of 29) African-derived fusions with novel PCa partners to ETV4, ERG and TMPRSS2, including FBXO7, LINC01525, GTF3C2 and NTNG1. Classified as a potential tumour suppressor gene, disruption of FBXO47 has been reported in breast, ovarian and renal cancers [58, 59], while to the best of our knowledge this is the first report of LINCO1525 disruption in any cancer.