PRKCQ-AS1, has not been studied in periodontitis, and our analysis showed that PRKCQ-AS1 may act as sponge of miR-141, miR-6512, miR-513c, and regulate the expression of CXCL1, PTGS2 (COX-2), THBS1 and PRKCQ. This evidence concerns the gene PTGS2 and periodontitis.