Moreover, application of known mitochondrial toxins in control SANCs, rotenone (complex I inhibitor), antimycin A (complex III inhibitor), and oligomycin A (adenosine triphosphate [ATP] synthase inhibitor), decreased the CaT amplitude and frequency, as well as impaired LCR (SI Appendix, Figs. S4 and S5), similar to the findings in HF SANCs. Here, CAT is linked to hydrops fetalis.