Our previous data have shown that the phosphorylation of CRMP2 at serine 522 (S522), threonine 514 (T514), or threonine 555 (T555) was downregulated in the hippocampus of pilocarpine-induced rat model of epilepsy at 1 day, 7 days, and 14 days after pilocarpine injection [29], suggesting that CRMP2 may play some roles in epilepsy. Here, DPYSL2 is linked to epilepsy.