Although the prognosis of IGFBP7 in TCGA‐GBM dataset was not significant, GBM patients with IGFBP7 higher expression levels had shored overall survival compared with GBM patients with IGFBP7 lower expression levels in CGGA, GSE13041 and GSE83300 three independent GBM cohorts (Figure 3A). The gene discussed is IGFBP7; the disease is glioblastoma.