SCUBE2 and cancer: The cancer genes are composed of genes that code for HER2 (HER2 and GRB7), oestrogen genes (ER, PGR, BCL2, and SCUBE2), proliferation genes (MKI67, STK15, BIRC5, CCNB1, and MYBL2), and invasion genes (MMP11 and CTSL2) as well as GSTM1, CD68, and BAG1 (Figure 6) [3].