The study included a small sample size. There was a lower baseline C-peptide level in the control group, compared to the intervention group. There was no group treated solely with vitamin D and insulin to determine if the positive results were related to allogeneic ADSC, vitamin D, or both. A longer follow-up is necessary to determine the long-term safety and efficacy of this intervention. The study only selected T1D patients with fasting C-peptide ≥0.3ng/ mL. This evidence concerns the gene INS and type 1 diabetes mellitus.