Liver function was almost within normal range, but renal dysfunction was observed: γ-glutamyl transpeptidase (γ-GTP), 25 U/L (13–64 U/L); alkaline phosphatase (ALP), 304 U/L (106–322 U/L); aspartate aminotransferase (AST), 25 U/L (13-30 U/L); alanine aminotransferase (ALT), 10 U/L (10–42 U/L); creatinine (CRE), 1.65 mg/dL (0.65–1.07 mg/dL); blood urea nitrogen (BUN), 52 mg/dL (8–20 U/L). The gene discussed is GPT; the disease is Abnormal renal physiology.