CXCL8 and Sepsis: IL8 can play a role in inducing chemotaxis and releasing reactive oxygen metabolites from neutrophils, and has been studied as a biomarker for neonatal sepsis.[24–26] However, IL8 was not significantly different according to sepsis in this study (yes: n = 13, 103.8 ± 158.0 vs no: n = 45, 190.4 ± 452.4 pg/mL, P = .948).