GD was highly enriched in IDHwt tumours (GD%, IDH1: 24%, IDH2: 9%, IDHwt: 63%, IDHwt vs IDH1 p = 0.0005, Fig. 1E), and HP was exclusive to this group (HP%, IDH1: 0%, IDH2: 0%, IDHwt: 37%, IDHwt vs IDH1 p = 8e-5, Fig. 1E). The gene discussed is IDH1; the disease is neoplasm.