The comparison of mucosal-adherent bacteria at tumor sites vs. unaffected mucosa in ApcMin/+NHE3−/− mice yielded relatively low-confidence data pointing to decreased relative abundances of Alistipes, Ruminiclostridium_5, Muribaculum, and Erisipelatoclostridium. Relatively little is known about the role of these genera in the pathogenesis of colonic inflammation and CRC. Here, SLC9A3 is linked to neoplasm.