The findings illustrated that GSDMC alterations were considerably correlated with the cancer-related genes in BRCA, including CASC8, POU5F1B, PVT1, TMEM75, MYC, CYRIB, RN7SKP226, CCDC26, CCAT1, and LINC00977 (Fig. 14B). This evidence concerns the gene POU5F1B and cancer.