Similarly, in GEP-NEN, no impact of sex, age, tumour size, lymph node status, presence of distant metastases, or tumour stage on SST4 expression was detected, and no difference in SST4 expression was observed between primary tumours and metastases or between tumours from patients who were still living at the end of the observation period and those who had died. The gene discussed is SSTR4; the disease is neoplasm.