SLE neutrophils and PBMCs with the lowest and highest IFIT3 expression (hereafter IFN-low and IFN-high, respectively) were then pooled according to cell type and IFIT3 expression (Figure 1B) and were used to screen SLE sera (n = 20) by immunoblotting to identify neutrophil autoantigens whose expression parallel that of IFIT3. Here, IFIT3 is linked to systemic lupus erythematosus.