Interestingly, while mice injected with the SOX10+ melanoma cell line MM383 showed similar expression of human GAPDH in all organs tested, we detected increased presence of hGAPDH in the brains of mice injected with SOX10– IGR-39 melanoma cells, compared with liver and lungs, suggesting a trend of preference in metastatic site for this subgroup (Figure 4E, P = 0.044). This evidence concerns the gene GAPDH and melanoma.