In fact, using conditioned media from sliced brain ex vivo culture as a chemoattractant in a Transwell migration assay with spatial separation in coculturing the MITF– melanoma cells together with ex vivo brain slice showed in unison that the SOX10– cells migrated with an increased rate toward the conditioned media and brain tissue, respectively, compared with the SOX10+ melanoma cells. Here, SOX10 is linked to melanoma.