PRTN3 and systemic sclerosis: In this respect, multiple case reports have described the association with sarcoidosis with SSc, Sjogren’s syndrome and SLE and besides ANA positivity, even the positivity for rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA) has been detected in a cohort of 41 sarcoid patients, respectively, in 22% and 8% of participants, despite the absence of rheumatoid arthritis [36].