Recombinant human IL-37 has protective effects against endotoxemia, acute lung and spinal cord injury, asthma, and myocardial infarction (Cavalli et al., 2016; Cavalli and Dinarello, 2018; Coll-Miró et al., 2016; Moretti et al., 2014; Wu et al., 2014; Li et al., 2015; Lunding et al., 2015; Ye et al., 2014). This evidence concerns the gene IL37 and myocardial infarction.