In individuals with obesity, high levels of cytokines including interleukin‐6 (IL‐6) and C‐reactive protein (CRP) may disrupt liver functions such as production of hepcidin which can lead to hepcidin‐related iron deficiency anaemia5, 6, 7, 8 and may lead to some types of liver diseases such as NAFLD and liver cancer.6, 9, 10, 11, 12. The gene discussed is HAMP; the disease is obesity due to melanocortin 4 receptor deficiency.