We also showed that overexpression of FLAG-BAF WT in NGPS patient cells was sufficient to rescue lamin A/C and emerin recruitment, and overexpression of BAF A12T in a wild-type background did not cause defects in the recruitment of these proteins, which explains the lack of disease phenotypes in NGPS parents who carry a BAF A12T heterozygous mutation (39,40). The gene discussed is BANF1; the disease is Nestor-Guillermo progeria syndrome.