The results illustrated that the cell proliferation and cell viability in the pcDNA3.1‐SAMD1 group were markedly higher relative to the pcDNA3.1‐NC group (Figure 4G,H, p < .05), and there was no significant difference between the pcDNA3.1‐NC group and the APS group. Here, SAMD1 is linked to autoimmune polyendocrinopathy.