The positive rates of anti‐B2GPI and ACA in the cell culture medium of the Control group, the Health group, and the APS group were further tested by ELISA, through which we observed that the positive rates of anti‐B2GPI and ACA in the APS group were higher than those in the Health group and the Control group (Figure 2D,E, p < .05). The gene discussed is APOH; the disease is autoimmune polyendocrinopathy.