FUT8 and Peritoneal Fibrosis: Based on our previous in vivo findings, there is increased activation of multiple signaling pathways, such as TGF‐β/Smad and PDGF/ERK, during renal interstitial and peritoneal fibrosis, and inactivation of these pathways by knockdown of FUT8 significantly attenuated fibrotic processes.14, 15, 24, 25